Piezo1 inactivation in chondrocytes impairs trabecular bone formation
نویسندگان
چکیده
In brief: Chondrocyte-specific ablation of the mechano-sensory Piezo1 results in substantially impaired formation secondary spongiosa during endochondral bone formation. The study explores this unexpected finding and show that mechano-sensing growth plate chondrocytes directly regulates trabeculae spongiosa.
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ژورنال
عنوان ژورنال: Yearbook of pediatric endocrinology
سال: 2021
ISSN: ['1662-3991', '1662-4009']
DOI: https://doi.org/10.1530/ey.18.5.14